Submitted by: sdemir   Date: 2009-05-14 11:37
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DESIRABLE SPECIFICATIONS FOR TOTAL ERROR, IMPRECISION, AND BIAS, DERIVED FROM BIOLOGIC VARIATION

Ricos C, Alvarez V, Cava F, Garcia-Lario JV, Hernandez A, Jimenez CV, Minchinela J, Perich C, Simon M. "Current databases on biologic variation: pros, cons and progress." Scand J Clin Lab Invest 1999;59:491-500.

 

CVI = within-subject biologic variation
CVG = between-subject biologic variation
I = desirable specification for imprecision
B = desirable specification for inaccuracy
TE = desirable specification for allowable total error

  Analyte Biological Variation Desirable specification
CVI CVg I(%) B(%) TE(%)
S- 11-Desoxycortisol 21.3 31.5 10.7 9.5 27.1
S- 17-Hydroxyprogesterone 19.6 50.4 9.8 13.5 29.7
U- 4-hydroxy-3-methoximandelate (VMA) 22.2 47.0 11.1 13.0 31.3
S- 5' Nucleotidase 23.2 19.9 11.6 7.6 26.8
U- 5'-Hydroxyindolacetate, concentration 20.3 33.2 10.2 9.7 26.5
S- α1-Acid Glycoprotein 11.3 24.9 5.7 6.8 16.2
S- α1-Antichymotrypsin 13.5 18.3 6.8 5.7 16.8
S- α1-Antitrypsin 5.9 16.3 3.0 4.3 9.2
S- α1-Globulins 11.4 22.6 5.7 6.3 15.7
U- α1-Microglobulin, concentration, first morning 33.0 58.0 16.5 16.7 43.9
P- α2-Antiplasmin 6.2 --- 3.1 --- ---
S- α2-Globulins 10.3 12.7 5.2 4.1 12.6
S- α2-Macroglobulin 3.4 18.7 1.7 4.75 7.56
U- α2-Microglobulin output, first morning 29.0 32.0 14.5 10.8 34.7
P- α-aminobutryic acid 24.7 32.3 12.4 10.2 30.5
S- α-Amylase 8.7 28.3 4.4 7.4 14.6
S- α-Amylase (pancreatic) 11.7 29.9 5.9 8.0 17.7
U- α-Amylase (pancreatic) 69.5 105.0 34.75 31.48 88.82
U- α-Amylase concentration, random 94.0 46.0 47.0 26.2 103.7
P- α-Carotene 24.0 65.0 12.0 17.3 37.1
S- α-Carotene 48.0 65.0 24.0 20.2 59.8
S- α-Fetoprotein(non hepatic carcinoma) 12.2 45.6 6.1 11.8 21.9
S- α-Tocopherol 13.8 15.0 6.9 5.1 16.5
S- Acid phosphatase 8.9 8.0 4.5 3.0 10.3
S- Acid phosphatase tartrate-resistant (TR-ACP) 8.0 13.3 4.0 3.9 10.5
S- Acid phosphatase prostatic activity (PAP) 33.8 --- 16.9 --- ---
P- Activated partial thromboplastine time 2.7 8.6 1.4 2.3 4.5
P- Adiponectin 18.8 51.2 9.4 13.6 29.1
S- Adenosine deaminase (ADA) 11.7 25.5 5.9 7.0 16.7
P- Alanine 14.7 55.8 7.4 14.4 26.6
S- Alanine aminopeptidase 4.1 --- 2.1 --- ---
S- Alanine aminotransferase (ALT) 19.40 41.6 9.7 11.48 27.48
S- Albumin 3.2 4.75 1.6 1.43 4.07
U- Albumin, concentration, first morning 36.0 55.0 18.0 16.4 46.1
U- Albumin, output, night urine 29.5 58.0 14.8 16.3 40.6
S- Albumin, glycated 5.2 10.3 2.6 2.9 7.2
S- Aldosterone 29.4 40.1 14.7 12.4 36.7
U- Aldosterone 39.4 40.1 19.7 14.05 46.56
S- Alkaline phosphatase 6.45 26.1 3.23 6.72 12.04
S- Alkaline phosphatase, bone 6.2 37.4 3.1 9.5 14.6
S- Alkaline phosphatase, liver 10.0 27.0 5.0 7.2 15.4
S- Alkaline phosphatase, placental 19.1 --- 9.6 --- ---
U- Ammonia, output, 24h 24.7 27.3 12.4 9.2 29.6
S- Amyloid A 25.0 61.0 12.5 16.5 37.1
S- Androstendione 15.8 38.8 7.9 10.47 23.51
S- Anion gap 9.5 10.1 4.8 3.5 11.3
P- Antithrombin III 5.2 15.3 2.6 4.0 8.3
S- Apolipoprotein A1 6.5 13.4 3.3 3.7 9.1
S- Apolipoprotein B 6.9 22.8 3.5 6.0 11.6
P- Arginine 19.3 34.1 9.7 9.8 25.7
S- Arilestearase activity, non inhibited 3.8 37.2 1.9 9.3 12.5
P- Ascorbate (Vitamin C) 20.0 21.0 10.0 7.3 23.8
S- Ascorbate (Vitamin C) 26.0 31.0 13.0 10.1 31.6
P- Asparagine 12.3 28.0 6.2 7.6 17.8
S- Aspartate aminotransferase (AST) 12.3 23.1 6.15 6.54 16.69
P- Aspartic acid 31.2 55.1 15.6 15.8 41.6
S- β-2-Microglobulin 5.9 15.5 3.0 4.1 9.0
P- β-Carotene 18.0 48.0 9.0 12.8 27.7
S- β-Carotene 36.0 39.7 18.0 13.4 43.1
S- β-Cryptoxantin 36.7 --- 18.4 --- ---
S- β-Globulins 10.1 9.1 5.1 3.4 11.7
B- Base excess 76.4 43.2 38.2 21.9 85.0
B- Basophile, count 28.0 54.8 14.0 15.4 38.5
S- Bilirubin total 21.8 28.4 10.90 8.95 26.94
S- Bilirubin conjugated 36.8 43.2 18.4 14.2 44.5
P- C Protein 5.6 55.2 2.9 13.9 18.7
S- C reactive protein 42.2 76.3 21.1 21.8 56.6
S- C reactive protein - high sensitivity 49.70 89.23 24.85 25.53 66.54
S- C3 Complement 5.2 15.6 2.6 4.1 8.4
S- C4 Complement 8.9 33.4 4.5 8.6 16.0
S- CA 125 antigen 24.7 54.6 12.4 15.0 35.4
S- CA 15.3 antigen 6.1 62.9 3.1 15.8 20.8
S- CA 19.9 antigen 16.0 130.5 7.98 32.87 46.03
S- CA 549 antigen 9.1 33.4 4.6 8.7 16.2
S- Calcium 2.1 2.5 1.05 0.82 2.55
S- Calcium, complexed 5.3 4.5 2.7 1.7 6.1
U- Calcium, concentration, 24h 27.5 36.6 13.8 11.4 34.1
S- Calcium, ionized 1.7 1.9 0.9 0.6 2.0
S- Calcium, protein bound 4.1 6.1 2.1 1.8 5.2
S- Calcium, ultrafiltrable 2.2 2.7 1.1 0.9 2.7
S- Carbohydrate deficient transferrin 7.1 38.7 3.6 9.8 15.7
B- CO2, total 4.0 4.8 2.0 1.56 4.86
S- Carcinoembryonic antigen (CEA) 12.7 55.6 6.4 14.3 24.7
S- Carnitine, Acyl-free 11.35 24.3 5.68 6.71 16.07
S- Carnitine, free 8.05 16.65 4.03 4.62 11.26
S- Carnitine, total 8.85 11.80 4.43 3.69 10.99
S- Ceruloplasmin (ferroxidase) 5.8 11.1 2.9 3.1 7.9
S- Chloride 1.2 1.5 0.6 0.5 1.5
S- Cholesterol 5.95 15.3 2.98 4.1 9.01
S- Cholinesterase, concentration 7.1 --- 3.6 --- ---
S- Cholinesterase, activity 6.1 18.2 3.1 4.8 9.8
P- Chromogranin A 12.8 26.3 6.4 7.3 17.9
P- Citrulline 21.4 43.9 10.7 12.2 29.9
S- Collagen type I C propeptide (PICP) 7.8 26.7 3.9 7.0 13.4
S- Collagen type I N propeptide (PINP) 7.4 57.3 3.7 14.4 20.5
S- Collagen type III N propeptide (PIIINP) 13.6 87.2 6.8 22.1 33.3
U- Color, first morning 30.9 47.4 15.5 14.1 39.6
P- Copper 8.0 19.0 4.0 5.2 11.8
S- Copper 4.7 13.6 2.35 3.6 7.47
P- Cortisol 21.7 46.2 10.85 12.76 30.66
S- Cortisol 15.2 38.1 7.6 10.26 22.8
S- C Peptide 16.6 23.2 8.3 7.1 20.8
S- Creatine kinase (CK) 22.8 40.0 11.4 11.5 30.3
S- Creatine kinase MB, % 6.9 48.2 3.5 10.8 16.5
S- Creatine kinase MB, activity 19.7 24.3 9.9 7.8 24.1
S- Creatine kinase MB, mass 18.4 61.2 9.2 14.88 30.06
S- Creatinine 5.95 14.7 2.98 3.96 8.87
U- Creatinine, concentration, 24h 24.0 24.5 12.0 8.6 28.4
U- Creatinine, concentration, first morning 23.2 25.7 11.6 8.7 27.8
U- Creatinine, concentration, random 36.3 32.4 18.2 12.2 42.1
U- Creatinine, output, 24h 11.0 23.0 5.5 6.4 15.4
S- C-Terminal telopeptide type I collagen (CTY I) 10.85 30.6 5.43 8.12 15.45
S- Cyfra 21.1 Antigen 22.2 31.1 11.1 9.6 27.9
P- Cystatin C 5.5 --- 2.8 --- ---
S- Cystatin C 5.0 13.0 2.5 3.48 7.61
P- Cysteine 5.9 12.3 3.0 3.4 8.3
P- Cystine 38.3 48.5 19.2 15.4 47.0
S- D-Dimer (MoM) 23.3 26.5 11.65 8.82 28.04
S- Dehydroepiandrosterone sulfate (DHEAS) 6.35 30.70 3.188 7.84 13.08
U- Deoxypyridinoline/creatinine, 24h 16.0 30.7 8.0 8.7 21.9
U- Deoxypyridinoline/creatinine, first morning 13.8 34.6 6.9 9.3 20.7
U- Deoxipyridinoline/minute, first morning 15.4 30.3 7.7 8.5 21.2
P- Dipeptidyl-peptidase IV (ACE) 8.2 14.5 4.1 4.2 10.9
S- Dipeptidyl-peptidase IV (ACE) 12.5 27.7 6.3 7.6 17.9
P- Elastase 12.4 15.1 6.2 4.88 15.11
B- Eosinophils, count 21.0 76.4 10.5 19.8 37.1
(B)Plat- Epinephrine 25.3 --- 12.7 --- ---
P- Epinephrine 48.3 --- 24.2 --- ---
B- Erythrocytes, count 3.2 6.3 1.6 1.7 4.4
B- Erythrocyte distribution wide 3.5 5.7 1.8 1.7 4.6
U- Estradiol 30.4 --- 15.2 --- ---
S- Estradiol 22.5 24.4 11.25 8.3 26.86
S- Estradiol, free 22.8 --- 11.40 --- ---
U- Estradiol, free 38.6 --- 19.3 --- ---
P- Factor V coagulation 3.6 --- 1.8 --- ---
P- Factor VII coagulation 6.8 19.4 3.4 5.1 10.7
P- Factor VIII coagulation 4.8 19.1 2.4 4.9 8.9
P- Factor X coagulation 5.9 --- 3.0 --- ---
S- Ferritin 14.2 15.0 7.1 5.2 16.9
P- Fibrinogen 10.7 15.8 5.4 4.8 13.6
(B)Erthry- Folate 12.0 66.0 6.0 16.8 26.7
S- Folate 24.0 73.0 12.0 19.2 39.0
S- Follicle stimulating hormone (FSH) 11.0 47.2 5.5 12.12 21.19
S- Fructosamine 3.4 5.9 1.7 1.7 4.5
S- Galactosyl hydroxylysine 11.8 25.8 5.9 7.1 16.8
P- γ-Fibrinogen 14.1 27.25 7.05 7.67 19.3
S- γ-Globulins 14.6 12.3 7.3 4.8 16.8
S- γ-glutamyltransferase (GGT) 13.4 42.15 6.7 11.06 22.11
S- Globulins, total 5.5 12.9 2.8 3.5 8.0
P- Glucose 4.5 5.8 2.3 1.8 5.5
S- Glucose 5.6 7.5 2.8 2.34 6.96
(B)Erythr- Glucose-6-phosphate-1-dehydrogenase (G6PDH) 32.8 31.8 16.4 11.4 38.5
B - spot Glucose-6-phosphate-1-dehydrogenase (G6PDH) 7.3 10.3 3.7 3.2 9.2
P- Glutamic acid 46.4 79.9 23.2 23.1 61.4
P- Glutamine 12.1 22.0 6.1 6.3 16.3
S- Glutathion peroxidase 7.2 21.7 3.6 5.7 11.7
P- Glycine 11.8 40.3 5.9 10.5 20.2
P- Haptoglobin 20.0 27.9 10.0 8.6 25.1
S- Haptoglobin 20.4 36.4 10.2 10.4 27.3
S- HDL cholesterol 7.3 21.2 3.65 5.61 11.63
S- HDL 1 cholesterol 5.5 27.2 2.8 6.9 11.5
S- HDL 2 cholesterol 15.7 40.7 7.9 10.9 23.9
S- HDL 3 cholesterol 7.0 14.3 3.5 4.0 9.8
B- Hematocrit 2.7 6.41 1.35 1.74 3.97
B- Hemoglobin 2.85 6.8 1.43 1.84 4.19
B- Hemoglobin A1 C 1.9 5.7 0.9 1.5 3.0
B- Hemoglobin A2 0.7 7.7 0.35 1.93 2.51
P- Histidine 9.7 27.2 4.9 7.2 15.2
P- Homocysteine 8.3 33.5 4.15 8.63 15.48
S- Hyaluronic acid 62.00 --- 31.00 --- ---
S- Hydroxybutyrate dehydrogenase 6.6 --- 3.3 --- ---
P- Hydroxyproline 34.5 56.7 17.3 16.6 45.1
U- Hydroxyproline/minute, first morning 36.1 38.8 18.1 13.2 43.0
U- Hydroxyproline/minute, second void 40.5 32.9 20.3 13.0 46.5
S- Immunoglobulin A 5.4 35.9 2.7 9.1 13.5
S- Immunoglobulin G 4.5 16.5 2.3 4.3 8.0
S- Immunoglobulin M 5.9 47.3 3.0 11.9 16.8
S- Immunoglobulins κ chains 4.8 15.3 2.4 4.0 8.0
S- Immunoglobulins λ chains 4.8 18.0 2.4 4.7 8.6
S- Inhibin B 10.0 25.0 5 6.73 14.98
S- Insulin 21.1 58.3 10.6 15.5 32.9
S- Insulin-like growth factor (IGF-1) 14.6 45.4 7.3 11.9 24.0
S- Insulin-like growth factor binding protein 3 (IGFBP-3) 10.1 63.9 5.1 16.2 24.5
S- Intercellular adhesion molecule-1 (ICAM-1) 1.9 21.0 1.0 5.3 6.8
(B)Leuc- Interferon receptor 14.0 20.0 7.0 6.1 17.7
S- Interleukin 1-β 30.0 36.0 15.0 11.7 36.5
S- Interleukin-8 24.0 31.0 12.0 9.8 29.6
S- Iron 26.5 23.2 13.3 8.8 30.7
P- Isoleucine 15.5 45.5 7.8 12.0 24.8
S- Kallicrein 6 11.80 27.6 5.9 7.5 17.24
B- Lactate 27.2 16.7 13.6 8.0 30.4
S- Lactate dehydrogenase (LDH) 8.6 14.7 4.3 4.3 11.4
S- Lactate dehydrogenase 1 isoform (LDH1) 2.3 8.3 1.2 2.2 4.1
S- Lactate dehydrogenase 2 isoform (LDH2) 3.3 2.4 1.7 1.0 3.7
S- Lactate dehydrogenase 3 isoform (LDH3) 2.8 3.8 1.4 1.2 3.5
S- Lactate dehydrogenase 4 isoform (LDH4) 5.9 5.3 3.0 2.0 6.9
S- Lactate dehydrogenase 5 isoform (LDH5) 8.0 9.6 4.0 3.1 9.7
P- Lactoferrin 11.8 23.7 5.9 6.6 16.4
S- LDL Cholesterol 7.8 20.4 3.9 5.46 11.9
P- LDL Cholesterol (oxidized) 21.0 50.0 10.5 13.6 30.9
S- LDL Cholesterol, small dense 9.1 20.0 4.55 5.49 13.0
S- LDL receptor mRNA 21.5 13.6 10.8 6.4 24.1
P- Leucine 14.8 44.0 7.4 11.6 23.8
B- Leukocytes count 11.4 21.3 5.73 6.05 15.49
S- Lipase 32.2 31.8 16.1 11.31 37.88
S- Lipoprotein (a) 20.8 18.1 10.4 6.9 24.1
P- Lutein 13.0 21.0 6.5 6.2 16.9
S- Lutein 23.7 --- 11.9 --- ---
S- Luteinizing hormone (LH) 23.0 27.4 11.5 8.94 27.92
P- Lycopene 22.0 33.0 11.0 9.9 28.1
S- Lycopene 40.1 33.0 20.1 13.0 ---
B- Lymphocytes, count 10.2 35.3 5.1 9.19 17.6
B- Lymphocytes CD4 25.0 --- 12.5 --- ---
P- Lysine 11.5 38.2 5.8 10.0 19.5
(B)Erythr- Magnesium 5.6 11.3 2.8 3.2 7.8
(B)Leuc- Magnesium 18.5 12.4 9.25 5.57 20.83
(B)Mon - Magnesium 18.1 20.3 9.1 6.8 21.7
S- Magnesium 3.6 6.4 1.8 1.8 4.8
U- Magnesium, ionized 1.9 5.1 1.0 1.4 2.9
U- Magnesium, output, 24h 38.3 37.6 19.2 13.4 45.0
(B)Erythr- Mean corpuscular hemoglobin (MCH) 1.4 5.2 0.7 1.35 2.5
(B)Erythr- Mean corpuscular hemoglobin concentration (MCHC) 1.06 1.2 0.53 0.4 1.27
(B)Erythr- Mean corpuscular volume (MCV) 1.4 4.85 0.7 1.26 2.42
(B)Plat- Mean platelet volume (MPV) 4.3 8.1 2.15 2.29 5.84
P- Metionine 14.7 43.4 7.4 11.5 23.6
B- Monocytes, count 17.8 49.8 8.9 13.2 27.9
S- Myeloperoxidase 36.0 30.0 18.0 11.7 41.4
S- Myoglobin 13.9 29.6 7.0 8.2 19.6
U- N-Acetyl Glucosaminidase, concentration, first morning 52.9 22.0 26.5 14.3 58.0
U- N-Acetyl Glucosaminidase/Creatinine 51.1 21.8 25.6 13.9 56.0
B- Neutrophyles, count 17.1 32.8 8.55 9.25 23.35
U- Nitrogen, output 13.9 24.2 7.0 7.0 18.4
B(Plat)- Norepinephrine 9.5 --- 4.8 --- ---
P- Norepinephrine 19.5 --- 9.8 --- ---
U- N-Telopeptide type I collagen 15.5 37.6 7.75 10.17 22.95
S- N-terminal (NT)-proBNP 10.0 16.0 5.0 4.7 13.0
P- Ornithine 18.4 54.9 9.2 14.5 29.7
P- Osmolality 1.3 1.5 0.7 0.5 1.6
Saliva- Osmolality 9.5 35.8 4.8 9.3 17.1
S- Osmolality 1.3 1.2 0.7 0.4 1.5
U- Osmolality, first morning 28.3 57.9 14.2 16.1 39.5
S- Osteocalcin 6.35 30.9 3.18 7.89 13.13
U- Oxalate, concentration, 24h 44.0 18.0 22.0 11.9 48.2
U- Oxalate, output, 24h 42.5 19.9 21.3 11.7 46.8
B- pCO2 4.8 5.3 2.4 1.8 5.7
B- pH [H+] 3.5 2.0 1.8 1.0 3.9
B- pH (pH units) 0.2 --- 0.1 --- ---
S- Paraoxonase 1 13.4 84.0 6.7 21.3 32.3
S- Paraoxonase 1 substrate inhibition (PON 4SI) 3.9 80.1 1.9 20.0 23.2
S- Paraoxonase, activity (salt stimulated) 8.0 86.4 4.0 21.7 28.3
P- Parathyroid hormone (PTH) 25.3 43.4 12.65 12.56 33.43
S- Parathyroid hormone (PTH) 25.9 23.8 13.0 8.8 30.2
S- Phenylacetate 6.6 25.2 3.3 6.5 12.0
P- Phenylalanine 9.5 40.6 4.8 10.4 18.3
S- Phosphate 8.15 10.8 4.08 3.38 10.11
U- Phosphate, output, 24h 18.0 22.6 9.0 7.2 22.1
Patient- Phosphate tubular reabsorption 2.7 3.3 1.4 1.1 3.3
S- Phospholipids 6.5 11.1 3.3 3.2 8.6
P- Plasminogen 7.7 --- 3.9 --- ---
B- Platelets, count 9.1 21.9 4.6 5.9 13.4
B- Platelet distribution wide 2.8 --- 1.4 --- ---
B- Plateletcrit 11.9 --- 6.0 --- ---
U- Porphobilinogen 17.0 31.0 8.5 8.8 22.9
U- Porphyrins (total) 40.0 --- 20.0 --- ---
(B)Leuc- Potassium 13.6 13.4 6.8 4.8 16.0
S- Potassium 4.6 5.6 2.3 1.81 5.61
U- Potassium, output 24.4 22.2 12.2 8.2 28.4
S- Prealbumin 10.9 19.1 5.5 5.5 14.5
S- Pregnancy-associated plasma protein A (PAPP-A) 12.6 14.0 6.3 4.71 15.1
P- Prolactin 39.2 65.1 19.6 19.0 51.34
S- Prolactin 23.0 35.0 11.5 10.5 29.4
P- Proline 17.0 104.4 8.5 26.4 40.5
P- Prolyl endopeptidase 16.8 13.9 8.4 5.5 19.3
S- Properdin factor B 9.5 11.2 4.7 3.7 11.5
S- Prostatic specific antigen (PSA) 18.1 72.4 9.1 18.7 33.6
S- Protein 2.75 4.7 1.38 1.36 3.63
S- Protein, glycated 0.9 11.6 0.5 2.9 3.7
U- Protein, output, 24h 35.5 23.7 17.8 10.7 40.0
P- Prothrombin time 4.0 6.8 2.0 2.0 5.3
U- Pyridinoline 19.4 23.6 9.7 7.6 23.6
B- Pyruvate 15.2 13.0 7.6 5.0 17.5
S- Receptor for advanced glycation end-products (RAGE) 14.6 56.5 7.3 14.59 26.63
B- Red cell distribution wide (RDW) 3.5 5.7 1.8 1.7 4.6
B- Reticulocyte highly fluorescent, count 10.0 62.0 5.0 15.7 24.0
B- Reticulocyte low fluorescent, count 1.6 4.9 0.8 1.3 2.6
B- Reticulocyte medium fluorescent, count 13.0 33.0 6.5 8.9 19.6
B- Reticulocyte, count 11.0 29.0 5.5 7.8 16.8
P- Retinol 6.2 21.0 3.1 5.5 10.6
S- Retinol 13.6 19.0 6.8 5.8 17.1
S- Rheumatoid factor 8.5 24.5 4.3 6.5 13.5
S- SCC antigen 39.4 35.7 19.7 13.3 45.8
P- S Protein 5.8 63.4 2.9 15.9 20.7
P- Selenium 12.0 14.0 6.0 4.6 14.5
B- Selenium 12.0 12.0 6.0 4.2 14.1
P- Serine 12.8 42.8 6.4 11.2 21.7
S- Sex hormone binding globulin (SHBG) 13.05 36.35 6.53 9.66 20.42
(B)Erythr- Sodium 1.8 12.4 0.9 3.1 4.6
(B)Leuc- Sodium 51.0 36.4 25.5 15.7 57.7
S- Sodium 0.6 0.7 0.3 0.23 0.73
B- Sodium Bicarbonate 4.0 4.8 2.0 1.6 4.9
S- Sodium Bicarbonate 4.8 4.7 2.4 1.7 5.6
Sweat- Sodium Chloride 15.0 25.0 7.5 7.3 19.7
U- Sodium, output, 24 h. 28.7 16.7 14.4 8.3 32.0
P- Soluble CD163 9.0 35.9 4.5 9.3 16.7
U- Specific gravity 0.4 1.0 0.2 0.27 0.60
Semen- Spermatozoa, concentration 26.8 56.4 13.4 15.6 37.7
Semen- Spermatozoa, morphology 19.6 44.0 9.8 12.0 28.2
Semen- Spermatozoa, progressive motility 15.2 32.8 7.6 9.0 21.6
Semen- Spermatozoa, fast progressive motility 18.8 51.8 9.4 13.8 29.3
Semen- Spermatozoa, total motility 18.4 29.8 9.2 8.8 23.9
Semen- Spermatozoa, vitality 10.3 25.8 5.2 6.9 15.4
S- Superoxide dismutase 17.1 10.5 8.6 5.0 19.1
(B)Erythr- Superoxide dismutase 12.3 4.9 6.2 3.3 13.5
P- Taurine 30.6 44.0 15.3 13.4 38.6
P- Testosterone 12.6 40.80 6.3 10.68 21.07
S- Testosterone 9.25 22.05 4.63 5.98 13.61
Saliva- Testosterone 17.3 28.8 8.7 8.4 22.7
U- Testosterone 25.0 --- 12.5 --- ---
S- Testosterone, free 9.3 --- 4.7 --- ---
U- Testosterone, free 51.7 --- 25.9 --- ---
S- Thyroglobulin 14.0 39.0 7.0 10.4 21.9
S- Thyroglobulin antibody 8.5 82.0 4.3 20.6 27.6
S- Thyroid peroxidase antibody 11.3 147.0 5.7 36.9 46.2
P- Thyroid stimulating hormone (TSH) 29.30 48.4 14.65 14.14 38.2
S- Thyroid stimulating hormone (TSH) 19.3 24.6 9.7 7.8 23.7
S- Thyrotropin receptor antibody 4.8 --- 2.4 --- ---
S- Thyroxine (T4) 4.9 10.9 2.5 3.0 7.0
P- Thyroxine, free (FT4) 7.1 9.1 3.55 2.89 8.74
S- Thyroxine, free (FT4) 5.7 12.1 2.9 3.3 8.0
S- Thyroxine binding globulin (TBG) 0.09 0.06 0.0 0.0 0.1
P- Tirosine 10.5 61.0 5.3 15.5 24.1
S- Tissue polypeptide antigen (TPA) 31.1 63.7 15.6 17.7 43.4
S- Tissue polypeptide specific antigen (TPS) 36.1 108.0 18.1 28.5 58.3
U- Total catecolamines, concentration, 24h 24.0 32.0 12.0 10.0 29.8
S- Transferrin 3.0 4.3 1.5 1.3 3.8
P- Treonine 17.9 33.1 9.0 9.4 24.2
S- Triglyceride 19.9 32.7 9.95 9.57 25.99
P- Triiodothyronine (T3) 9.4 18.5 4.7 5.19 12.94
S- Triiodothyronine (T3) 6.9 12.3 3.45 3.53 9.22
S- Triiodothyronine, free (FT3) 7.9 17.6 4.0 4.8 11.3
P- Troponin I 37.1 179.2 18.55 45.75 76.36
S- Troponin I 14.05 63.75 7.03 16.32 27.91
S- Troponin T 30.5 90.0 15.3 23.7 48.9
P- Tryptophan 22.7 152.6 11.4 38.6 57.3
S- Tumor Necrosis Factor-a (TNF-a) 43.0 29.0 21.5 13.0 48.4
S- Urate 8.6 17.5 4.3 4.87 11.97
U- Urate, output, 24h 16.8 14.4 8.4 5.53 19.39
S- Urea 12.1 18.7 6.05 5.57 15.55
U- Urea, output, 24h 17.4 25.4 8.7 7.7 22.1
P- Valine 10.6 40.1 5.3 10.4 19.1
U- Vanilmandelic Acid concentration, 24h 22.2 47.0 11.1 13.0 31.3
S- Vascular cell adhesion molecule-1 (VCAM-1) 5.2 16.0 2.6 4.2 8.5
P- Vascular endotelial growth factor 14.1 18.1 7.1 5.7 17.4
B- Vascular endotelial growth factor 14.3 28.8 7.2 8.0 19.8
S- Vascular endotelial growth factor 10.7 47.6 5.4 12.2 21.0
P- Vitamin B1 4.8 12.0 2.4 3.2 7.2
B- Vitamin B2 (Riboflavin) 5.8 10.0 2.9 2.9 7.7
(B)Eryth- Vitamin B2 (Riboflavin) 6.4 11.0 3.2 3.2 8.5
(B)Eryth- Vitamin B2 status (gluthation reductase activation) 5.2 40.0 2.6 10.1 14.4
(B)Eryth- Vitamin B12 15.0 69.0 7.5 17.7 30.0
(B)Eryth- Vitamin B6 14.0 24.0 7.0 6.9 18.5
B- Vitamin B6 20.0 34.0 10.0 9.9 26.4
(B)Eryth- Vitamin E (Tocopherol) 7.6 21.0 3.8 5.6 11.9
(B)Eryth- Vitamin K (Phylloquinone) 38.0 44.0 19.0 14.5 45.9
S- VLDL Cholesterol 27.6 --- 13.8 --- ---
P- Von Willebrand factor 2.5 27.3 1.3 6.9 8.9
S- Water 3.1 0.1 1.6 0.8 3.3
S- Zeaxanthine 34.7 --- 17.4 --- ---
S- Zinc 9.3 9.4 4.7 3.3 11.0
P- Zinc 11.0 14.0 5.5 4.5 13.5

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Tagler: Acceptable Target,  Bias,  Biological Variation,  Imprecision,  Total Analytical Error,  Total Error

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